"The room was big and clean, with a nice equipted kitchen and and living area on the ground floor with balcony."
Hbit from Israel
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"We appreciated all the extra touches that set this resort apart like fresh muffins daily, dove bars nightly, and bottled water."
Ruth S from United States
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"Loved the pool and happy hour and proximity to great restaurants! Room was also very spacious and well maintained."
Emily from United States
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Santa Maria Suites Resort is a 4-star luxury property in Key West with two outdoor heated pools surrounded by luscious gardens.
Luxurious Two-Bedroom Suites
Lavishly appointed, two-bedroom suites at Santa Maria Suites Resort feature designer kitchens, airy living rooms, 48" flat screen TVs, patios and balconies, and spa-like bathrooms with rainfall showers. Each bedroom includes a king-size bed, work desk, spacious closet, and separate bathroom.
Upscale Latin Dining
The Milagro Restaurant at Santa Maria Suites offers an upscale Latin dining experience with contemporary cuisine. Guests can head to Louie's Backyard for Bahamian Conch Chowder with Bird Pepper Hot Sauce served on a multilevel deck.
Garden-Enclosed Heated Pools
The property offers two garden-enclosed heated pools with chilled towels, frozen drinks, bottled water and poolside service. Guests enjoy distinctive resort amenities like fruit smoothies by the pool and a fitness center with Cybex equipment.
Beach and Island Adventures
Day trips are available to exotic islands where a 250-year-old military fort, white sand beaches and turquoise seas invite exploration. The best beach on Key West is at Fort Zachary Taylor, a beautiful 54-acre park along the shoreline.
Prime Old Town Location
Located in Duval, Santa Maria Suites Resort offers a great location in Old Town close to Mallory Square, Key West festivals, and Duval Street nightlife. Ernest Hemingway's Home, where the Nobel Prize-winning author's spirit remains in lush gardens and six-toed cats, is within walking distance.
“This resort stands out for its spacious, well-appointed suites that cater especially to families. The lush, garden-enclosed pools create a tranquil, almost magical atmosphere, a true escape so close to Duval Street. I especially appreciate the thoughtful touches like poolside refreshments and turndown service, which elevate the stay from comfortable to truly memorable.”
Olivia StoneManaging Editor at Familyresort
Choose Your Family Room Type
Choose from a range of family rooms including doubles, suites, and special family packages with meals and free cancellations
Two-Bedroom Villa Garden View
2 persons
905 sq. feet
1 King-size bed
Air conditioning
Balcony
room details
Two-Bedroom Villa Pool View
2 persons
905 sq. feet
1 King-size bed
Air conditioning
Balcony
room details
Two-Bedroom Suite Pool View
2 persons
960 sq. feet
1 King-size bed and 1 Sofa bed
Air conditioning
Heating
room details
Show all rooms
Room Availability & Price Calendar
Find availability and check prices for your dates now!
October 2026 - October 2027
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Choose dates to see prices
Check-in/ Check-out
Facilities
Our resorts offer tailored amenities to ensure your family’s comfort and unforgettable experiences
Facilities: Perfect
9.3/10Review score
General
Non-smoking rooms
Paid Wi-Fi
Parking
Safe deposit box
24-hour reception
VIP check-in/ -out
No pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Luggage storage
Smoke detectors
Electric vehicle charging station
Fire extinguishers
Key card access
Sports & Fitness
Fitness centre
Wind surfing
Diving
Snorkelling
Cycling
Fishing
Guest Parking
Private parking is possible on site (reservation might be needed) at USD 20 per day.
Services
Housekeeping
Laundry
Dry cleaning
Tours/Ticket assistance
Grocery shopping service
Welcome drink
Happy hour
Dining
Restaurant
Poolside snack bar
Business
Fax/Photocopying
Children
Cots
Facilities for people with disabilities
Toilet for disabled
Bathroom for disabled
Spa & Leisure
Heated swimming pool
Outdoor swimming pool
Beach access
Beach umbrellas
Sun loungers
Live entertainment
Garden area
Shallow end
Room features
Air conditioning
Heating
Soundproofed rooms
Sitting area
Patio
Terrace
Garden furniture
Ironing facilities
Bathroom
Washing machine
Free toiletries
Self-catering
Electric kettle
Dryer
Cookware/ Kitchen utensils
Media
Flat-screen TV
AM/FM alarm clock
Show more
Dining Onsite
Indulge in a delightful array of dining experiences at Santa Maria Suites Resort, featuring everything from modern Caribbean and Mexican flavors to fresh seafood in a stunning open-air setting. Each venue captures the essence of Key West's vibrant culinary scene, perfect for travelers seeking a mix of relaxation and indulgence.
Milagro Restaurant
Upscale Latin dining with Caribbean and Mexican influences
Ambiance
Modern and romantic, featuring one of the best views in town
Key Offerings
Savor contemporary Latin dishes with an elegant flair, complemented by specialty cocktails in a casual setting
Reservation
Recommended
Open for dinner
Amigo's
Mexican casual dining
Ambiance
Lively atmosphere perfect for people-watching on Duval Street
Key Offerings
Enjoy a cold Corona with delicious Baja fish burritos in a relaxed outdoor setting
Reservation
Not needed
Hours vary
Japanese Bistro
Casual dining with fresh sushi offerings
Ambiance
Relaxed space featuring a fresh sushi bar, great for unwinding
Key Offerings
Freshly made sushi and other Japanese delights in a friendly, casual environment
Reservation
Not needed
Hours vary
Santa Maria Suites Resort Location
1401 Simonton Street, Key West, 33040,
Explore Key West
Explore Key West
Top Attractions
Activities
Dining
Entertainment
Southernmost Point
5 minutes walking
A famous buoy marking the southernmost point in the continental U.S. A must-see for photos and local lore.
Key West Butterfly and Nature Conservatory
6 minutes walking
A serene habitat featuring hundreds of butterflies and exotic birds. Perfect for nature lovers and families.
The Ernest Hemingway Home and Museum
12 minutes walking
Hemingway's former residence, showcasing his life and works. Guided tours available to enhance your visit.
Truman Little White House
25 minutes walking
Historic site where President Truman vacationed. Offers insights into presidential history through guided tours.
Snorkeling at Western Dry Rocks
5 minutes drive
Thrilling snorkeling adventures await at Western Dry Rocks, known for vibrant coral reefs and abundant marine life.
Yoga at the Beach
4 minutes walking
Relaxing beach yoga sessions available at nearby beaches. Perfect for unwinding and enjoying ocean views.
Biking around the Island
5 minutes driving
Bike rentals nearby offer a fun way to explore Key West's scenic routes and attractions at your own pace.
Key West Fishing Charters
5 minutes driving
Exciting fishing charters available for all skill levels. Experience the thrill of fishing in one of the best locations.
Southernmost Beach Cafe
4 minutes walking
Casual beachfront restaurant with fresh seafood and tropical drinks. Ideal for a laid-back dining experience.